Christophe Guignabert Selected Research

Aminorex

12/2022

Identifying new drugs associated with pulmonary arterial hypertension: A WHO pharmacovigilance database disproportionality analysis.

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Christophe Guignabert Research Topics

Disease

45	Pulmonary Hypertension 03/2022 - 05/2005
42	Pulmonary Arterial Hypertension 12/2022 - 05/2008
20	Vascular Remodeling 01/2022 - 05/2005
19	Hypoxia (Hypoxemia) 11/2021 - 05/2006
14	Inflammation (Inflammations) 01/2021 - 07/2005
9	Fibrosis (Cirrhosis) 01/2022 - 07/2013
8	Hypertrophy 01/2021 - 02/2008
7	Familial Primary Pulmonary Hypertension 07/2021 - 05/2006
7	Neoplasms (Cancer) 10/2019 - 08/2011
6	Disease Progression 01/2021 - 08/2011
5	Hyperplasia 01/2021 - 05/2005
4	Lung Diseases (Lung Disease) 01/2021 - 01/2018
4	Pulmonary Fibrosis (Fibrosing Alveolitis) 12/2018 - 11/2017
3	Heart Failure 01/2022 - 05/2012
3	Pleural Effusion (Pleural Effusions) 10/2020 - 11/2016
3	Interstitial Lung Diseases (Interstitial Lung Disease) 10/2020 - 11/2017
3	Pneumonia (Pneumonitis) 01/2020 - 12/2013
3	Systemic Scleroderma (Systemic Sclerosis) 01/2019 - 11/2017
3	Idiopathic Pulmonary Fibrosis 01/2019 - 01/2016
3	Right Ventricular Hypertrophy 01/2019 - 07/2013
2	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 10/2012
2	Hypertension (High Blood Pressure) 11/2021 - 10/2018
2	Lung Injury 01/2020 - 01/2018
2	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2019 - 01/2018
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2016 - 05/2012
2	Arteritis 08/2015 - 03/2011
1	Drug-Related Side Effects and Adverse Reactions 12/2022
1	Genomic Instability 01/2022
1	Body Weight (Weight, Body) 01/2021
1	Asthma (Bronchial Asthma) 01/2021
1	Obesity 01/2021

Drug/Important Bio-Agent (IBA)

16	MonocrotalineIBA 01/2022 - 05/2005
8	Dasatinib (BMS 354825)FDA Link 12/2022 - 05/2012
8	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2005
8	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 04/2006
7	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 01/2021 - 09/2008
6	CytokinesIBA 01/2021 - 02/2014
4	Platelet-Derived Growth FactorIBA 01/2022 - 11/2017
4	LigandsIBA 10/2021 - 05/2008
4	LeptinIBA 01/2021 - 10/2012
4	Therapeutic UsesIBA 01/2020 - 12/2013
4	Tyrosine Kinase InhibitorsIBA 01/2019 - 05/2012
4	Pharmaceutical PreparationsIBA 10/2018 - 01/2016
4	Serotonin (5 Hydroxytryptamine)IBA 02/2017 - 04/2006
3	CollagenIBA 01/2022 - 02/2008
3	Hormones (Hormone)IBA 01/2021 - 02/2015
3	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2021 - 03/2011
3	Imatinib Mesylate (Gleevec)FDA Link 10/2020 - 10/2012
3	Bone Morphogenetic Protein ReceptorsIBA 01/2020 - 09/2009
3	Semaxinib (SU5416)IBA 01/2020 - 01/2018
3	Macrophage Migration-Inhibitory FactorsIBA 01/2020 - 12/2018
3	Bleomycin (Blenoxane)FDA LinkGeneric 12/2018 - 11/2017
3	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 04/2014 - 03/2009
2	Biological ProductsIBA 12/2022 - 12/2018
2	Activin Receptors (Activin Receptor)IBA 10/2021 - 01/2019
2	Bosentan (Tracleer)FDA Link 01/2021 - 08/2015
2	bosutinibIBA 10/2020 - 11/2016
2	Type II Bone Morphogenetic Protein Receptors (Bone Morphogenetic Protein Receptor Type II)IBA 01/2020 - 05/2008
2	Adenosine (Adenocard)FDA LinkGeneric 01/2020 - 01/2018
2	AntibodiesIBA 01/2019 - 11/2017
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 02/2014
2	Growth Differentiation Factor 2IBA 01/2019 - 01/2019
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2019 - 08/2011
2	nintedanibIBA 01/2019 - 01/2016
2	Endothelin-1 (Endothelin 1)IBA 01/2019 - 08/2015
2	Vasodilator Agents (Vasodilators)IBA 01/2019 - 02/2017
2	PotassiumIBA 10/2018 - 12/2009
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 06/2014
2	ambrisentan FDA Link 02/2017 - 08/2015
2	Transcription Factors (Transcription Factor)IBA 01/2016 - 02/2015
2	Interleukin-6 (Interleukin 6)IBA 06/2014 - 04/2014
2	ElastinIBA 03/2011 - 02/2008
2	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 12/2009 - 05/2005
1	Dexfenfluramine (Redux)IBA 12/2022
1	Appetite Depressants (Anorectics)IBA 12/2022
1	benfluorex (S 780)IBA 12/2022
1	Amphetamine (Amfetamine)FDA LinkGeneric 12/2022
1	AminorexIBA 12/2022
1	Methamphetamine (Desoxyn)FDA LinkGeneric 12/2022
1	Illicit Drugs (Recreational Drugs)IBA 12/2022
1	FenfluramineIBA 12/2022
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2022
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2022
1	Interleukin-2 (IL2)IBA 01/2022
1	Hypochlorous Acid (Hypochlorite)IBA 01/2022
1	HydantoinsIBA 01/2022
1	Fibrillar CollagensIBA 01/2022
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2022
1	LysophospholipidsIBA 11/2021
1	Angiotensin IIIBA 11/2021
1	NSC 23766IBA 01/2021
1	activin AIBA 01/2021
1	Inhibins (Inhibin)IBA 01/2021
1	urate transporterIBA 01/2021
1	sacubitril and valsartan sodium hydrate drug combinationIBA 01/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021

Therapy/Procedure

16	Therapeutics 01/2022 - 12/2013
2	Lung Transplantation 10/2012 - 10/2004
1	Endarterectomy (Thromboendarterectomy) 03/2022
1	Injections 01/2022